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SC-100 Interview Questions and Answers

Navneet Kumar

|

07 Apr, 2025

SC-100 Interview Questions and Answers
Image Credit: Cloud360 Training

 

Are you preparing for the SC-100: Microsoft Cybersecurity Architect Expert certification or an interview for a senior cybersecurity role? You’re in the right place. This blog compiles the top 50 SC-100 interview questions with correct answers and explanations, aligned with the exam’s focus areas and real-world architectural scenarios. 

 

What is the SC-100 Exam? 

The SC-100 certification validates your expertise in designing and evolving cybersecurity strategies using Microsoft technologies. It’s a capstone expert-level exam that assumes experience across identity, device, data, app, and infrastructure security. 

 

Domains Covered 

  • Design a Zero Trust strategy and architecture 

  • Evaluate security posture 

  • Design security solutions for infrastructure 

  • Design security operations 

 

Top 50 SC-100 Interview Questions with Answers 

1. What is the role of a Microsoft Cybersecurity Architect? 

Answer: To design and evolve comprehensive security strategies that align with business needs using Microsoft security solutions. 

 

2. What are the core pillars of Zero Trust architecture? 

Answer: Verify explicitly, use least privilege access, and assume breach. 

 

3. What tools are used to implement Zero Trust in Microsoft environments? 

Answer: Azure AD, Conditional Access, Defender for Endpoint, Microsoft Entra, Microsoft Purview, and Microsoft Sentinel. 

 

4. How would you assess an organization’s current security posture? 

Answer: Use Microsoft Secure Score, Defender for Cloud recommendations, and Microsoft Compliance Manager. 

 

5. How does Microsoft Secure Score help cybersecurity architects? 

Answer: It provides a measurable security posture score with actionable recommendations. 

 

6. How do you prioritize security initiatives in a large organization? 

Answer: Based on business risk, threat likelihood, and compliance requirements. 

 

7. What is Conditional Access and where does it fit in a Zero Trust model? 

Answer: It enforces policies based on identity signals and conditions—central to Zero Trust. 

 

8. How would you design identity protection in a hybrid environment? 

Answer: Use Azure AD Identity Protection, MFA, PIM, and integration with on-premises Active Directory. 

 

9. What is Microsoft Defender XDR? 

Answer: A unified threat protection suite covering endpoint, identity, email, and cloud apps. 

 

10. What’s the difference between Microsoft Sentinel and Defender XDR? 

Answer: Sentinel is a SIEM/SOAR solution for correlating and responding to events across the organization, while Defender XDR provides protection and detection at the workload level. 

 

11. What is Microsoft Entra? 

Answer: A suite that includes Azure AD, Entra Permissions Management, and Entra Verified ID for identity governance. 

 

12. How do you design a secure access strategy for third-party contractors? 

Answer: Use B2B collaboration, Conditional Access, and Just-in-Time access through PIM. 

 

13. What is a workload identity? 

Answer: An identity used by applications or services to access other services securely. 

 

14. What role does Microsoft Defender for Cloud play in architecture? 

Answer: It provides CSPM (Cloud Security Posture Management) and CWPP (Cloud Workload Protection Platform) capabilities. 

 

15. What’s the best way to segment networks in Azure? 

Answer: Use virtual networks, subnets, NSGs, ASGs, and Azure Firewall. 

 

16. How would you protect data at rest in Azure? 

Answer: Use storage encryption, disk encryption, and customer-managed keys with Azure Key Vault. 

 

17. How would you detect threats in Microsoft 365 workloads? 

Answer: Use Microsoft Defender for Office 365 and Microsoft Sentinel connectors. 

 

18. What’s the importance of role-based access control (RBAC) in Azure? 

Answer: RBAC enforces the principle of least privilege by assigning permissions based on roles and scope. 

 

19. How can you enforce compliance across subscriptions? 

Answer: Use Azure Policy, Management Groups, and Blueprints. 

 

20. What’s the function of Microsoft Compliance Manager? 

Answer: It helps manage compliance requirements with assessments and improvement actions. 

 

Advanced / Scenario-Based Questions 

21. How would you secure a multi-cloud environment with Microsoft tools? 

Answer: Integrate AWS and GCP into Defender for Cloud and Sentinel; use Entra Permissions Management. 

 

22. What would your approach be to respond to a ransomware incident? 

Answer: Isolate affected systems, analyze with Defender XDR, contain with Sentinel playbooks, and conduct root cause analysis. 

 

23. How do you prevent lateral movement after an identity compromise? 

Answer: Use MFA, Conditional Access, Defender for Identity, and microsegmentation. 

 

24. How would you monitor insider threats? 

Answer: Use Microsoft Purview Insider Risk Management, Sentinel, and auditing. 

 

25. What’s a secure way to manage secrets in cloud-native apps? 

Answer: Store them in Azure Key Vault and restrict access via managed identities. 

 

26. How do you manage Bring Your Own Device (BYOD) security? 

Answer: Enforce Conditional Access, compliance policies with Intune, and MAM without enrollment. 

 

27. What’s the benefit of using Defender for IoT? 

Answer: It provides deep visibility into unmanaged IoT/OT devices and detects threats. 

 

28. How would you architect security for a DevOps pipeline? 

Answer: Integrate Defender for DevOps, secret scanning, access controls, and vulnerability management. 

 

29. How do you perform risk analysis for new business initiatives? 

Answer: Evaluate threat models, compliance implications, and use Microsoft Threat Modeling Tool. 

 

30. What’s your approach to data classification and labeling? 

Answer: Use Microsoft Purview Information Protection and auto-labeling policies. 

 

Security Architecture and Governance 

31. What is a security baseline? 

Answer: A predefined configuration standard aligned with organizational or regulatory policies. 

 

32. How do you enforce encryption across Azure resources? 

Answer: Use policies that audit or deny unencrypted services. 

 

33. What is Zero Trust for apps? 

Answer: Ensuring only verified apps can access corporate resources using Defender for Cloud Apps. 

 

34. How do you secure legacy systems in cloud migration? 

Answer: Isolate, monitor via Defender for Endpoint, and apply compensating controls. 

 

35. What is continuous access evaluation (CAE)? 

Answer: Real-time policy enforcement in Azure AD for access decisions. 

 

36. How do you use log analytics in security architecture? 

Answer: Ingest logs to Sentinel for correlation, detection, and automation. 

 

37. What’s your approach to handling third-party SaaS security? 

Answer: Monitor via Defender for Cloud Apps and integrate with SSO and Conditional Access. 

 

38. What is Identity Governance in Microsoft Entra? 

Answer: It ensures users have appropriate access with access reviews, entitlement management, and lifecycle workflows. 

 

39. How do you use threat intelligence in architecture? 

Answer: Integrate with Microsoft Sentinel, Defender XDR, and third-party feeds. 

 

40. What’s the importance of architecture reviews? 

Answer: Regular reviews help align with new threats, business changes, and compliance updates. 

 

Interview-Ready Final 10 

41. How do you balance user experience with security? 

Answer: Apply risk-based policies, SSO, and adaptive access controls. 

 

42. What’s your approach to hybrid cloud security strategy? 

Answer: Use centralized tools like Defender for Cloud, unified logging, and hybrid identity. 

 

43. How would you respond to a compliance audit request? 

Answer: Use Compliance Manager reports and Microsoft Purview records. 

 

44. How do you design for resilience in a security solution? 

Answer: Redundancy, failover, DR, and defense-in-depth. 

 

45. What tools help you track and report incidents? 

Answer: Microsoft Sentinel, Microsoft Purview, Defender XDR. 

 

46. How do you ensure DevSecOps in your architecture? 

Answer: Integrate security scanning tools, access controls, and compliance checks in pipelines. 

 

47. How do you protect privileged identities? 

Answer: Use PIM, Conditional Access, auditing, and break-glass accounts. 

 

48. What KPIs would you track for security architecture? 

Answer: Secure Score, incident response time, policy compliance, MFA usage. 

 

49. How do you approach business-aligned security design? 

Answer: Collaborate with stakeholders, align controls with risk appetite and regulatory needs. 

 

50. What makes a good cybersecurity architecture? 

Answer: It’s layered, adaptive, resilient, aligned with business needs, and based on Zero Trust principles. 

 

The SC-100 exam and related interviews demand deep architectural thinking, practical understanding of Microsoft tools, and a strong Zero Trust mindset. This set of 50 SC-100 interview questions with answers provides a holistic foundation for real-world security architecture and certification success.

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